The CORE Multi-Drug Screen Test is a competitive immunoassay that is used to screen for the presence of drugs of abuse in urine.  It is a chromatographic absorbent device in which drugs or drug metabolites in a sample compete with drug / protein conjugate immobilized on a porous membrane for a limited number of antibody /dye conjugate binding sites.  The test device employs a unique combination of monoclonal and polyclonal antibodies to selectively identify drugs of abuse in urine with a high degree of confidence. In the procedure, the absorbent end of the test device is inserted into the urine sample. The urine is absorbed into the device by capillary action, mixes with the antibody/dye conjugate, and flows across the pre-coated membrane. When sample drug levels are below the target cutoff sensitivity of the test, antibody/dye conjugate binds to the drug/protein conjugate immobilized in the Test Region (T) of the device. This produces a colored Test Band that, regardless of intensity, indicates a negative result. When sample drug levels are at or above the target cutoff, the free drug in the sample binds to the antibody/ dye conjugate, preventing the antibody/dye conjugate from binding to the drug/protein conjugate immobilized in the Test Region (T) of the device. This prevents the development of a distinct colored band, indicating a positive sample. In either case, a colored Control Band is produced in the Control Region (C). This band serves as a built-in quality control device that demonstrates antibody recognition and reactivity as well as confirmation that the test is complete.

CORE Multi-Drug Screen Test card is with two separate test regions for the targeted drugs, Marijuana and Methamphetamine. Each test region contains:

·Monoclonal anti-drug antibody/colloidal gold conjugate in a protein matrix containing        

·  0.1% sodium azide coated in the sample path.

·Drug derivative/protein conjugate immobilized as a line in the test region.

·Goat anti-mouse antibody immobilized as a line in the control region.

·Sample transfer pipette, complete use instructions and technical background information.